TLC BioSciences is a late clinical-stage specialty pharmaceutical company dedicated to the research, development, and commercialization of novel nanomedicines that maximize the potential of its proprietary lipid-assembled drug delivery platform (LipAD®). TLC’s deep experience with liposome science allows TLC to combine onset speed and benefit duration, and improve active drug concentrations while decreasing unwanted systemic exposures. TLC’s BioSeizer® technology is designed to enable local sustained release of therapeutic agents at the site of disease or injury; its NanoX® active drug loading technology is designed to alter the systemic exposure of the drug, potentially reducing dosing frequency and enhancing distribution of liposome-encapsulated active agents to the desired site; new early-stage assets include gene therapy and lipid nanoparticle (LNP) treatments with the potential to regenerate cells. These technologies are versatile in the choice of active pharmaceutical ingredients and scalable with respect to manufacturing. TLC has a diverse, wholly owned portfolio of therapeutics that target areas of unmet medical need in orthopedics and pain management.
1997 | TLC is founded by Dr. Keelung Hong |
2002 | Lipo-Dox® is approved for treatment of ovarian cancer |
2004 | Lipo-Dox® is approved for treatment of breast cancer |
2018 | TLC is listed and traded on the Nasdaq Global Market (symbol: TLC) in 2018 |
2020 | TLC reports positive results from Phase 2 trial of TLC590 for postsurgical pain |
2021 | InspirMed™ Inc., is established to specialize in the development of inhalable liposome formulation programs such as TLC19 for severe acute and chronic pulmonary diseases. |
2021 | New Drug Application of Liposomal Amphotericin B in India is approved |